The Phospho-RYR3(Ser160) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ryanodine receptor 3, and RYR3. This antibody recognizes Human, and Mouse antigen. The Phospho-RYR3(Ser160) Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Function: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca2+ release by other calcium channels. Calcium channel that mediates Ca2+-induced Ca2+ release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling.
Subunit Structure: Homotetramer. Heterotetramer with RYR2. Interacts with CALM (By similarity). Interacts with FKBP1A. Interacts with SELENON (By similarity).
Similarity: The calcium release channel activity resides in the C-terminal region while the remaining part of the protein resides in the cytoplasm. Belongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily